Suboptimal bowel cleansing prior to colonoscopy impairs the efficacy and safety of
the procedure. A new system for intracolonic cleansing has been developed, which includes
a disposable catheter device that is inserted through the working channel of a standard
colonoscope and an irrigation unit with predefined pressure and flow rate. The aim
of the current study was to assess the safety and efficacy of this novel system for
the improvement of bowel cleansing during colonoscopy. A total of 42 patients with
suboptimal bowel preparation were systematically allocated, in a 1:1 ratio, to either
the study group (JetPrep system, n = 21) or the control group (syringe irrigation,
n = 21). The cleansing efficacy was evaluated using a segmental scoring scale to rate
the bowel preparation level before and after irrigation. One patient from the study
group was excluded from the efficacy analysis due to treatment with both techniques.
The JetPrep system was significantly superior to syringe irrigation (P = 0.0001). No adverse events were reported. This study suggests that the safety profile
of the JetPrep system is comparable to standard irrigation and shows that the device
significantly improves suboptimal bowel preparation.